Pramiplexole Makes me so Sick

[gridlock]

Does anyone else get the extreme nauseous feeling on Prami?

Its seems i get hot, dizzy and want to chuck up on just a .25ml dosage. I was curious to see if anybody else suffers the same feeling from it and what was done to overcome it?

 

[Jello]

I did, but I kept reading that a lot of the sides would go away if I increased the dose. So as dumb as that sounded to me I tried it and by the 3rd night all was good Try running it at .5 for a few nights and see what happens.

 

[aesop]

for me the .5mg pre bed seems to have less sides and more benefit than lower dosing. Have been sleeping like a rock, with some weird dreams.

 

[EDED]

its weird ive never heard this many complaints about Caber/dostinex but so many threads about prami sides.

why is this one so much better? and one must tolerate so much sides when caber does the samething???

 

[thomasfouraker]

I feel super sick to my stomach on .5mg. I sleep hard for about 4 hours then the rest of the night I am up it seems like every other hour.
How long until prami kicks in for you guys?

Better than milking my nips though.

 

[iprimate]

I feel nauseous on pramipexole also. I have actually thrown up from it. That was from 1mg. I will try again with .25mg.

I don't get any nausea or vomitting from bromocriptine or cabergoline.

 

[iprimate]

I feel super sick to my stomach on .5mg. I sleep hard for about 4 hours then the rest of the night I am up it seems like every other hour.
How long until prami kicks in for you guys?

Better than milking my nips though.

You can get generic (pharmaceutical grade) cabergoline or bromocriptine. These are also effective in lowering prolactin.

 

[1bigun11]

its weird ive never heard this many complaints about Caber/dostinex but so many threads about prami sides.

why is this one so much better? and one must tolerate so much sides when caber does the samething???

Prami is cheaper than caber and also boosts hgh production to up to 4x the natural release during the night. Best used right before bed, then you sleep through the nausea if any. People run Prami year round, not necessarily only to treat prolactin sides. Or you can use only as needed for 19nor puffy nipples/gyno.

 

[Macro]

Does anyone else get the extreme nauseous feeling on Prami?

Its seems i get hot, dizzy and want to chuck up on just a .25ml dosage. I was curious to see if anybody else suffers the same feeling from it and what was done to overcome it?

this is hypoglycemia, most likely.... eat some carbs...

 

[Macro]

I did, but I kept reading that a lot of the sides would go away if I increased the dose. So as dumb as that sounded to me I tried it and by the 3rd night all was good Try running it at .5 for a few nights and see what happens.

this is often the case.

may not be with nausea.

the other "ill feeling issue" is usually hypoglycemia (which for some reason people are not all that familar with)--- and there one just needs to eat more and longer/slower digesting carbs before bed (or when dosing-- it can also happen during day time, especially when using other glucose clearing agents)...

higher dose can knockout hypo issue (when its due to dopamine surge- as opposed to GH)

 

[jay_dub]

Macro, what would you consider a "higher dose" to avoid nausea? Over 1mg?

 

[Macro]

Macro, what would you consider a "higher dose" to avoid nausea? Over 1mg?

generally. However, keep in mind the blood sugar issue, once plasma levels become eve, - which varies but usually by day 14, that becomes a relative non issue. but in the first day and days of dosing it can be significant and one needs to be aware of it. to differentiate between nausea and low blood sugar.

 

[gridlock]

this is hypoglycemia, most likely.... eat some carbs...

nah it definitley wasnt. I used to go hypglycemic a lot so i know the feeling inside out. I know it was the prami as it wasnt the first time it happened when all other factors were equal bar the prami

 

[epoxy]

i take .5mg a day but i swear to god if i dont take it with some food it will make me feel like i'm going to vomit.

 

[Macro]

nah it definitley wasnt. I used to go hypglycemic a lot so i know the feeling inside out. I know it was the prami as it wasnt the first time it happened when all other factors were equal bar the prami

when you say all other factors being equal... agree that prami may have been the factor that tipped you over... it does not mean that prami (via dopaminergic activity) caused the nausea. though prami can cause nausea directly.... its less common..

hypo and hyperglycemia are common issues with anabolic steroids (they can blunt insulin sensitivity and increase glucose clearance) THEN adding gh (in this case spiked natural gh production), decreasing water intake (dopaminergic activity will decrease thirst and hunger cues), etc (effects of prami) can be tipping points in either direction (depending on food (fructose, sucrose, tfa's, saturated vs. polyunsaturates..etc...), water, supplements- stims, glucose sensitizers, glucose clearance agents, electrolytes, exposure to high heat, how much cardio you are doing, meal timing, speed of food consumption, etc... can lead to tipping in either direction...

using SERMS and/or aromatase inhibitors will also have impacts on blood glucose...

 

[klowndog]

IT HURTS!!!

Been taking .25 ml befopre bed, sleeping like a fucking baby. My girl doesn't wan tto give up no more sex for a while though. "It hurts" she said. No nausea here.

 

[Macro]

Been taking .25 ml befopre bed, sleeping like a fucking baby. My girl doesn't wan tto give up no more sex for a while though. "It hurts" she said. No nausea here.

prami can increase time and frequency of such "activities" (for both sexes... perhaps more so with women). Lubrication (exogenous) and proper hydration are key to avoiding "over use" syndrome.

 

[gridlock]

when you say all other factors being equal... agree that prami may have been the factor that tipped you over... it does not mean that prami (via dopaminergic activity) caused the nausea. though prami can cause nausea directly.... its less common..

hypo and hyperglycemia are common issues with anabolic steroids (they can blunt insulin sensitivity and increase glucose clearance) THEN adding gh (in this case spiked natural gh production), decreasing water intake (dopaminergic activity will decrease thirst and hunger cues), etc (effects of prami) can be tipping points in either direction (depending on food (fructose, sucrose, tfa's, saturated vs. polyunsaturates..etc...), water, supplements- stims, glucose sensitizers, glucose clearance agents, electrolytes, exposure to high heat, how much cardio you are doing, meal timing, speed of food consumption, etc... can lead to tipping in either direction...

using SERMS and/or aromatase inhibitors will also have impacts on blood glucose...

agreed however what i'm saying is the prami time and time again (not on this one instance HAS CAUSED me to feel nasueous (not hypoglycemic) regardless of whether it is less common, when they ran the clinical trials for this, in the case of people that suffered restless leg syndrome, the most common sides were nausea, dizziness and the sweats, which can lead you to think that people are hypo when they describe to you, but it wasnt the case and was reported as a direct result of administration of prami

 

[Macro]

agreed however what i'm saying is the prami time and time again (not on this one instance HAS CAUSED me to feel nasueous (not hypoglycemic) regardless of whether it is less common, when they ran the clinical trials for this, in the case of people that suffered restless leg syndrome, the most common sides were nausea, dizziness and the sweats, which can lead you to think that people are hypo when they describe to you, but it wasnt the case and was reported as a direct result of administration of prami

agree, but its actually as likely that such is hyperglycemia (though why no one seems to realize this...), though may be due to dopaminergic action OR GH elevation.

sides of GH elevation (endogenous and exogenous) (fromdrugstore.com)
Typical side effects of growth hormone medication include headache, nausea, vomiting, fatigue, muscle pain or weakness, swelling of the extremities, hypoglycemia (low blood sugar), blurred vision, burning/tingling sensations, dizziness, nervousness, numbness, carpal tunnel syndrome, or serious allergic reaction.